From Nature 449, 253. " Hiking the ups and downs of the science trail." by Paul Smaglik
My wife developed a hiking litmus test, which could also be applied to scientific careers. If we woke up in the morning eager to walk again, no matter how much we had been beaten up by the elements the previous day, we would continue. That feeling of excitement never subsided, no matter how cold, wet, sore and dirty we got. So too in science, if you no longer have that sensation of hope, curiosity and anticipation, it might be time to stop — or at least to look for another job.
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